Results of prospective trials have often overestimated the outcomes of patients with severe peritonitis. Mar 27, 2014 abdominal sepsis represents the hosts systemic inflammatory response to bacterial peritonitis. The patient had previously been diagnosed as having enteric fever from a neighbouring health facility. Thus, the effective treatment of abdominal sepsis requires surgical control of the leakage from the hollow viscus, removal of infected or necrotic contaminated tissue, drainage of the pus or release of. Abdominal sepsis occurs as result of intraabdominal. Sepsis does not have a characteristic clinical picture, and its diagnosis is based in a high suspect index and the verification. For patients with septic shock, antibiotics should be administered as soon as. Jun 30, 2016 abdominal infections are an important challenge for the intensive care physician. Severe sepsis and therapy with activated protein c.
Mortalidad sepsis severa 912 % shock septico 2040%. A 32yearold female presented with fever and generalised malaise to a rural hospital in ghana. The principle treatment of intraabdominal source of sepsis in critically ill patients is control of the underlying cause of the source it self. The challenge of intraabdominal sepsis sciencedirect. Abstract sepsis is a syndrome complicating any severe infection, and it is triggered by a variable systemic host response, leading to generalized tissue damage. It is associated with significant morbidity and mortality rates, and is the second most common cause of sepsisrelated mortality in the intensive care unit. In an era of increasing antimicrobial resistance, selecting the appropriate regimen is important and, with new drugs coming to the market, correct use is important more than ever before and abdominal infections are an excellent target for antimicrobial stewardship programs. The term sepsis encompasses a spectrum of disease ranging from systemic inflammatory response syndrome sirs to severe sepsis and multiple organ failure. Antimicrobial therapy should be initiated once a patient receives a diagnosis of an intraabdominal infection or once such an infection is considered likely. Treatment of patients who have complicated intraabdominal infections iais by adequate management, has generally been described to produce satisfactory results. The principle treatment of intra abdominal source of sepsis in critically ill patients is control of the underlying cause of the source it self. Doo r, kasper d, panzo r, chtiais, grusby m, sayegh, tzianabus a.
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